منابع مشابه
Evaluation of radiopharmaceuticals sequestered by acutely damaged myocardium.
Eighteen radiopharmaceuticals were screened in a small-animal model as potential infarct-localizing agents. Twelve of the 18 compounds were labeled with 99mTc, four with 203Hg, one with 131I, and one with either 203Hg or 125I. The model used heat-induced myocardial lesions in the rat. The absolute concentration within the lesion and also the activity ratios of injured myocardium to normal heart...
متن کاملMyometrial cells induce angiogenesis and salvage damaged myocardium.
Characteristically, uterine myometrial cells (MCs) are proliferative, inducing angiogenesis within the female reproductive organ. We evaluated whether MCs implanted into myocardium could also induce angiogenesis and restore heart function after injury. MCs were isolated from the adult rat uterus and cultured for three studies: 1) Intracellular VEGF levels were measured in MCs cultured with prog...
متن کاملCell survival and redistribution after transplantation into damaged myocardium
A hybrid approach to support cell survival and decrease cell escape Cell transplantation has become an attractive option for cardiac regenerative therapy. However, poor cell survival and extensive redistribution throughout the body can drastically affect the outcome and safety of cell therapy. Although various approaches have been attempted to support the survival and engraftment of implanted c...
متن کاملPreferential uptake of intravenously administered hyaluronidase (Hyalosidase) by damaged rat myocardium.
The induction of myocardial infarction in rats by ligation of the left-anterior coronary artery was confirmed by measurement of increased plasma levels of creatine kinase, aspartate aminotransferase and lactate dehydrogenase. Using this model system it has been established that intravenous administration of 125I-labelled hyaluronidase to rats resulted in a preferential uptake of the enzyme by d...
متن کاملResident nestin+ neural-like cells and fibers are detected in normal and damaged rat myocardium.
The present study examined whether nestin+ neural-like stem cells detected in the scar tissue of rats 1 week after myocardial infarction (MI) were derived from bone marrow and/or were resident cells of the normal myocardium. Irradiated male Wistar rats transplanted with beta-actin promoter-driven, green fluorescent protein (GFP)-labeled, unfractionated bone marrow cells were subjected to corona...
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ژورنال
عنوان ژورنال: Journal of Electrocardiology
سال: 2007
ISSN: 0022-0736
DOI: 10.1016/j.jelectrocard.2007.05.025